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Surface Characteristics Control the Attachment and Functionality of (Chimeric) Avidin

2018

The physical adsorption (physisorption) of proteins to surfaces is an important but incompletely understood factor in many biological processes and is of increasing significance in bionanotechnology as well. Avidin is an important protein because of strong avidin–biotin binding, which has been exploited in numerous applications. We have undertaken thorough experimentation on the physisorption of avidin, to chemically different flat surfaces of Si and graphite and also to the curved version of the latter, on multiwalled carbon nanotubes (MWNTs) of different diameters. The difference in the behavior of avidin on Si versus graphite is drastic; on Si, avidin deposits as single globular tetramer…

Surface (mathematics)kolloidit02 engineering and technologyemulsions010402 general chemistry01 natural sciencessurfactantsinterface componentsAdsorptionPhysisorptioncolloidsElectrochemistryKemia - Chemical sciencesGeneral Materials SciencepolymeeritpolymersemulsiotSpectroscopyta114biologyChemistrySurfaces and Interfaces021001 nanoscience & nanotechnologyCondensed Matter Physicsproteins0104 chemical sciencesbiology.proteinBiophysicsnanoparticlesnanohiukkasetproteiinit0210 nano-technologyAvidinLangmuir
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